

The binding of each oxygen molecule makes it easier for the next to bind, (affinity increases with each oxygen molecule bound) so the curve has to be curved and it shifts in either direction.ġ1. Why does the oxyhemoglobin dissociation curve not form a straight line? Left shift: increased Hb-O2 affinity (O2 stays bound to Hb and cannot diffuse into the tissues) and right-shift: decreased Hb-O2 affinity (O2 has trouble staying bound to Hb and prefers to be in the tissues).ġ0. What does a left shift or a right shift on the oxyhemoglobin curve represent? How many oxygen binding sites are there for hemoglobin?ĩ. CO binds to cytochrome c oxidase in mitochondria and to myoglobin in heart/skeletal muscle.Ĩ. CO-Hb shifts the oxyhemoglobin dissociation curve to the left, thereby impairing the dissociation of O2 from hemoglobin, impairing O2 delivery to the tissues. Presence of CO-Hb reduces oxyhemoglobin saturation and decreases blood O2-carrying capacity. What are the three mechanisms of CO-induced hypoxia? Place the patient in a hyperbaric oxygen chamber.īinds to heme iron in hemoglobin with an affinity 250x that of O2, creating carboxyhemoglobin (CO-Hb) and causing tissue hypoxia.ħ. What is the most effective methods of treating carbon monoxide poisoning? Smoke inhalation in fires, automobile exhaust fumes, faulty/poorly ventilated charcoal, kerosene, or gas stoves, and temporary use of electrical generators.ĥ. Give them 100% oxygen as soon as possible. As a Respiratory Therapist, in general, when patients are suspected of carbon monoxide poisoning, what is the first thing that must be done to treat this patient? What is an abbreviation for carbon monoxide?ģ. It is harmful and can be very dangerous if a person inhales too much of this gas.Ģ. Hyperbaric oxygen therapy might also be used or pregnant women to protect unborn babies from damage from carbon monoxide poisoning.Carbon Monoxide is a colorless, odorless, nonirritating gas produced by the incomplete combustion of any carbon-containing material. It helps protect heart and brain tissue from carbon monoxide damage. Hyperbaric oxygen therapy might be used for severe carbon monoxide poisoning.

This helps replace carbon monoxide with oxygen in the blood. The air pressure in the chamber is 2 to 3 times higher than usual. It involves breathing pure oxygen in a chamber for a set amount of time. This is called hyperbaric oxygen therapy. People who can't breathe on their own might be put on a machine that breathes for them, called a ventilator. This helps oxygen reach organs and tissues. In the emergency room, standard treatment involves breathing pure oxygen through a mask placed over the nose and mouth. These include headache, dizziness, nausea, shortness of breath, weakness and confusion. Call 911 or emergency medical help if you or someone with you has symptoms of carbon monoxide poisoning. In this case, each person gets oxygen through a lightweight, clear hood. Hyperbaric oxygen therapy also can be given to more than one person in a large room.
